<p>This article provides an overview of role of the family doctor and dentist in the prevention of chronic lupus erythematosus. One of the most important problems of modern medicine is diseases of the oral mucosa. Despite the fact that a disease such as lupus erythematosus is an autoimmune and rheumatic disease, it is also manifested in the oral cavity, which develops the prerequisites for cooperation between a family doctor and a dentist [1, 6-10] A characteristic feature of chronic lupus erythematosus is the diversity of first manifestations course and clinical manifestations. Typically, the disease begins with one or more symptoms. Clinical picture at the onset of the disease may differ strikingly from the "classical" descriptions of this disease, which often causes diagnostic difficulties not only for general practitioners, but also for rheumatologists [5]. According to 2010 data, the prevalence of the disease in the world it is 3.3–8.8 per 100, 000 children [1]. Lupus erythematosus affects mainly girls and young women, approximately 80% of patients with lupus erythematosus are women. Lupus erythematosus rarely begins in children under 5 years of age, an increase in incidence is observed from the age of 8–9 years, and the culmination occurs at the age of 14–25 years (average age of beginning is - 11–12 years) [1, 3, 4, 12]. Currently, family doctors and dentists are increasingly encountering this pathology, and therefore methods of its treatment are being improved, and much attention is paid to methods of preventing this disease [6, 7, 10, 11].</p>