Several datasets are available (all datasets contain participant ID, randomised allocation, COVID/flu cohort and site): (1) Main dataset (data collected at all study visits including allocation details, baseline demographics and vaccination details); (2) Solicited events from electronic participant diaries dataset; (3) Unsolicited and medically attended events dataset; (4) Influenza immunogenicity from blood samples dataset (Influenza A H3N2, Influenza A H1N1, Influenza B Victoria, Influenza B Yamagata); (5) COVID immunogenicity from blood samples dataset (Ig from ECLIA Roche assay, IgG from ELISA Nexelis assay, viral neutralising assay (VNA; neutralisation dilution at 50%, ND50; neutralising factor at 50%, NF50)); (6) COVID immunogenicity from saliva samples dataset (IgG and IgA in binding antibody units (BAU)/ml and normalised OD units