The concept of “satisfaction with one’s own sexual life” gives a new impetus to the study of psychological well-being of an individual in general and success in professional activity of businessmen in particular as components of personal maturity, positive sanogenic personal potential. The article presents modern works of foreign and domestic scientists on the problems of human sexuality (biological, medical and sexological, general psychological and other aspects); well-being of an individual. The main aspects of the problem of satisfaction with one’s own sexual life as sexual well-being of an individual and the problems of psychological well-being of an individual are considered. Research assumptions are formulated. The theoretical and methodological basis of the study of the problem of satisfaction with one’s own sexual life in the context of psychological well-being of businessmen is determined. The results of a theoretical and empirical study of the current psychological problem of the interrelationship between satisfaction with one’s own sexual life with psychological well-being of modern domestic businessmen are presented. Proof of the interrelationship between sexual satisfaction with the psychological well-being of businessmen was carried out using Pearson, Tau-b Kendall and Spearman correlation analyses and the results were presented. Positive rather high correlations, which are revealed by three types of correlation analysis, enable to state that psychological well-being of businesspeople depends on their sexual development and their satisfaction with their sexual lives.</em