Effects of Na-Ca exchange on cartilage swelling and fluid transport

Abstract

The generalized triphasic theory has been developed for describing mechanoelectrical behaviors of charged-hydrated-soft tissues containing multi-electrolytes. In the present work, this theory is used to study the problem Na super(+)-Ca super(++) exchange in cartilage. In particular, the effects of Na super(+)-Ca super(++) exchange on the one-dimensional swelling behavior of the tissues is investigated by determining the transport of Na super(+) and Ca super(++) across the throughout the layer of tissue, and by calculating the stresses, strains and fluid velocities within the tissue induced by the Na super(+)-Ca super(++) exchange. The stresses strains and fluid velocities within the tissue were calculated using a finite-difference method. Calculation results showed that the strain distribution within the specimen was non-monotonic and nonlinearly dependent on the local concentrations of Na super(+) and Ca super(++) present

    Similar works