cIAP1 (cellular inhibitor of apoptosis 1), the olfactory system, homeostasis, terminal differentiation, cell deathprohibitionCHAPTER 1. INTRODUCTION 1
1.1 cIAP1 1
1.1.1 IAPs (inhibitor of apoptosis proteins) 1
1.1.1.1 Structure of IAP family
1.1.1.2 Roles of IAP family
1.1.2 cIAP1 3
1.1.2.1 Functions of cIAP1
1.1.2.2 cIAP1, cIAP2 and XIAP
1.2 The olfactory system 5
1.2.1 The anatomy of the olfactory system 5
1.2.1.1 Olfactory epithelium
1.2.1.2 Olfactory bulb
1.2.2 Regeneration of the olfactory system 7
1.3 Purpose of the project 8
CHAPTER 2. MATERIALS AND METHODS 9
CHAPTER 3. RESULTS 12
3.1 cIAP1 KO mice 12
3.2 Protein activation 12
3.2.1 cell-death related proteins
3.3 Morphological observation 14
3.3.1 Cell death in the OE
3.3.2 Synaptic connection in the OB
3.4 Behavioral observation 20
CHAPTER 4. DISCUSSION 21
CHAPTER 5. FURTHER STUDIES 25
REFERENCES 26
ABSTRACT IN KOREAN 33MasterdCollectio
