위장에서의 다중 위액 채취 및 헬리코박터 파일로리 검출을 위한 pH 센서 내장형 자기 구동 캡슐

Abstract

Helicobacter pylori, Magnetically driven capsule, pH sensor, Multiple sampling, Gastrointestinal diseaseNⅠ. Introduction 1 1.1 Gut Microbiome in Human Body 1 1.2 Characteristics of H. pylori 1 1.3 Diagnosis of H. pylori Infection and Its Limitations 2 1.4 Limitations of Microorganisms Sampling Methods 2 1.5 Purpose of Research 4 Ⅱ. Design Concept & Working Process 5 2.1 Magnetically Driven Capsule for Multiple Sampling and Detection of H. pylori 5 2.2 EMA (Electromagnetic Actuation) System 6 2.3 pH Sensor for Detection of H. pylori 7 Ⅲ. Materials & Methods 10 3.1 Materials 10 3.2 H. pylori Culture 10 3.3 pH Sensor 11 3.4 Fabrication of pH Sensor-embedded Magnetically Driven Capsule 14 3.5 Experiment Setup 16 3.6 Magnetic Driving Test Using 6-coils EMA System 18 3.7 Phantom Test 18 3.8 Ex-vivo Test 19 Ⅳ. Results & Discussions 20 4.1 Characterization of pH Sensor 20 4.2 pH Sensor-embedded Magnetically Driven Capsule 23 4.3 Phantom Test 26 4.4 Ex-vivo Test 29 Ⅴ. Conclusion 32MasterdCollectio