Zebrafish, simultaneous EEG measurement, drug screeningprohibitionAbstract i
List of Contents ii
List of tables iv
List of figures v
1 INTRODUCTION 1
2 RECORDING SYSTEM FOR ADULT ZEBRAFISH 2
Concept of Recording System 2
Experimental Design and Method 2
2.2.1 Animal preparation and maintenance 2
2.2.2 Experimental set-up 3
2.2.3 Statistical methods 5
Result 5
3 RECORDING SYSTEM FOR LARVAL ZEBRAFISH 14
Concept of Recording System 14
Experimental Design and Method 14
3.2.1 Animal preparation and maintenance 14
3.2.2 Design and fabrication of microfluidic chip 15
3.2.3 Test of liquid exchangeability 16
3.2.4 Experimental set-up 17
3.2.5 Statistical methods 17
Result 18
3.3.1 Result of simulation and experiment to test liquid exchangeability 18
3.3.2 Result of EEG recording 18
4 DISCUSSIONS 24
5 CONCLUSION 25
REFERENCES 26MasterdCollectio
