Nanostarch is unique in that it is highly soluble, thermally stable, non-toxic and inex�pensive. Hence, it is utilized in numerous well-established applications, including drug
delivery, cosmetics, textiles, foods, and enhanced oil recovery (EOR). These applications
take advantage of the special functions that can be achieved through modifcations to the
structure and properties of native starch. The most common method for the preparation of
nanostarch with a relatively higher crystallinity and stability is acid hydrolysis. Technically,
the properties of nanostarch are highly dependent on several factors during the hydrolysis
process, such as the acid, concentration of acid, reaction time, reaction temperature, and
source of starch. The production of nanostarch with desired properties requires a detailed
understanding on each of the factors as they are inevitably afected the physical and chemi�cal properties of nanostarch. Hence, it is vital to incorporate optimization technique into
the production process to achieve the full potential of nanostarch. Therefore, the current
review comprehensively elaborates on the factors that afect acid hydrolysis as well as the
optimization techniques used in the preparation of nanostarch