The hospital was established as a channel for hospital services to every level of society thathas several marketing strategies defined to be able to maintain a good response from customers, so the hospital must have an effective program to retain oldcustomers. The marketing mix is a solution for patient problems, in obtaining pleasant,comfortable serviceand good communication from the hospital to customers. Loyalty level that displays the need to have a high sense of loyalty, as well as having a beneficial effect on the healthcareorganization. The purpose of this study was to determine the relationship between themarketing mix and patient loyalty in the outpatient installation polyclinic at the Nyi AgengSerang Kulon Progo Regional General Hospital. This research is a quantitative research approach cross-sectional. The sample in this study was 110 outpatient polyclinic patients selected by purposive sampling. There search was conducted in June-July 2023 at Nyi AgengSerang Hospital, Kulon Progo. Data analysis univariate, bivariate and multivariate with ChiSquare statistical tests and Multiple Linear Regression statistical tests. The results showedthat there was a relationship between the marketing mix of places and patient loyalty with a p-value of 0.002. There is a relationshipbetween the marketing mix of people and patient loyalty with a p-value of 0.000. There is a relationship between the marketing mix processand patient loyalty with a p-value of 0.007. and multivariate analysis shows that the marketing mix variables place, people and process statistically have a joint influence onpatient loyalty and the variable that has the greatest influence is the marketing mix variable people with a p-value of 0.004. There is a significant relationship between marketing mix place, people, process and patient loyalty
