Akasaki, Y

Eguchi, A

Fujimoto, K

Fujio, K

Hirosawa, K

Inomata, T

Kuwahara, M

Midorikawa-Inomata, A

Miura, M

Murakami, A

Nagino, K

Nakamura, M

Okumura, Y

Shokirova, H

Sung, Jaemyoung

Yanagawa, A

Zhu, J

English

Lehigh Valley Health Network: LVHN Scholarly Works

Lehigh Valley Health Network LVHN Scholarly Works USF-LVHN SELECT Diagnostic ability of maximum blink interval with Ocular Surface Disease Index score for dry eye disease Jaemyoung Sung Lehigh Valley Health Network, jaemyoung.sung@lvhn.org T Inomata K Hirosawa M Nakamura Y Okumura See next page for additional authors Follow this and additional works at: https://scholarlyworks.lvhn.org/select-program  Part of the Medical Education Commons Published In/Presented At Sung, J., Inomata, T., Hirosawa, K., Nakamura, M., Okumura, Y., Midorikawa-Inomata, A., Miura, M., Fujio, K., Akasaki, Y., Fujimoto, K., Zhu, J., Eguchi, A., Nagino, K., Kuwahara, M., Shokirova, H., Yanagawa, A., & Murakami, A. (2023). Diagnostic ability of maximum blink interval with ocular surface disease index score for dry eye disease [Poster]. Presented as USF Capstone Project. This Poster is brought to you for free and open access by LVHN Scholarly Works. It has been accepted for inclusion in LVHN Scholarly Works by an authorized administrator. For more information, please contact LibraryServices@lvhn.org. Authors Jaemyoung Sung, T Inomata, K Hirosawa, M Nakamura, Y Okumura, A Midorikawa-Inomata, M Miura, K Fujio, Y Akasaki, K Fujimoto, J Zhu, A Eguchi, K Nagino, M Kuwahara, H Shokirova, A Yanagawa, and A Murakami This poster is available at LVHN Scholarly Works: https://scholarlyworks.lvhn.org/select-program/1051 Conclusion• Concomitant use of MBI and OSDI may be sufficient to substitute TFBUT as a remote screening tool.• This may have implications in improving the worsening prevalence of DED, particularly through reducing barriers to healthcare.• Additionally, the implementation of this finding in the context of mHealth may positively affect the outreach of this screening process to younger, working populations.Problem StatementThis research aims to assess the diagnostic capability of maximum blink interval (MBI) as a substitute for the tear film break up time (TFBUT) used in traditional dry eye disease (DED) diagnosis.Results• 365 participants were included in this study and 252 (69.0%) were diagnosed with DED through traditional diagnostic standards (Table 2). • The results indicate that the use of MBI and J-OSDI may be useful in screening purposes, suggested by the high specificity and positive-predictive value (92.9% and 96%; Table 1). • ROC results for MBI+OSDI was comparable to TFBUT+OSDI (.938 vs .954, respectively) (Fig. 1). Table 1. Precision rate detected between MBI with J-OSDI and TFBUT with J-OSDI. cTable 2. Characteristics of study participants.    Fig 1. Receiver operating characteristic (ROC) curve for detection of dry eye disease (DED). Diagnostic ability of maximum blink interval with Ocular Surface Disease Index score for dry eye diseaseSung,J.1,2, Inomata, T. 2, Hirosawa, K.2, Nakamura, M. 2, Okumura, Y. 2, Midorikawa-Inomata, A. 2, Miura, M. 2, Fujio, K. 2, Akasaki, Y. 2, Fujimoto, K. 2, Zhu, J. 2, Eguchi, A. 2, Nagino, K. 2, Kuwahara, M. 2, Shokirova, H. 2, Yanagawa, A. 2, Murakami, A. 21. University of South Florida, Morsani College of Medicine, Tampa, FL USA2. Juntendo University, Department of Ophthalmology, Tokyo, JapanIntroduction• DED is one of the most common ocular surface diseases, leading to decreased visual acuity, work productivity, and quality of life.• Mainstay of DED diagnosis requires TFBUT measurement, necessitating an in-person visit.• MBI is positively correlated with TFBUT, which could act as a non-invasive proxy. • Using DryEyeRhythm®, an in-house app for DED, MBI’s performance was compared to traditional diagnosisMethods• A retrospective cross-sectional observational study at Juntendo University Hospital, Tokyo, Japan. • Patients with clinically diagnosed DED (MBI + J-OSDI) were included in the study.  • Participants were assessed for best-corrected visual acuity, intraocular pressure (IOP), and Dry Eye-Related Quality-of-Life Score (DEQS) questionnaire, TFBUT, corneal staining scores (CFS), and Schirmer I test. • Pearson correlation coefficients were estimated among MBI, DEQS, TFBUT, and Schirmer test Ι. • ROC analysis was conducted to examine the diagnostic efficacy of MBI for DED. 

Diagnostic ability of maximum blink interval with Ocular Surface Disease Index score for dry eye disease

https://scholarlyworks.lvhn.org/cgi/viewcontent.cgi?article=2054&context=select-program

Diagnostic ability of maximum blink interval with Ocular Surface Disease Index score for dry eye disease

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