Research progress on the mechanism of microtubule inhibitors in vascular neoplastic diseases

Abstract

Neovascular diseases involve multiple systems and organs and are a major category of diseases characterized by angiogenesis, including tumors, cardiovascular diseases and eye diseases. Microtubule inhibitors are a class of natural or synthetic drugs which inhibit neovascularization and block neovascularization through changing the state of microtubules. They may induce apoptosis and block cell cycle by affecting angiogenesis related genes and cytokines