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Abstract
Background: The sternal lift by Vacuum Bell (VB) is effective, as largely demonstrated by its intraoper-ative use during surgical procedure to elevate the sternum during the Nuss procedure routinely. Indeed, the thoracic remodelling during VB application is comparable to post-surgical scenario, and suitable to compare cardiovascular parameters of the two different thoracic configurations immediately. Objective: We would quantify and correlate preoperative parameters which determine the severity of the pectus excavatum (PE), and the cardiovascular effects at the baseline. Than we would assess the cardio-vascular changes during VB positioning, mimicking the immediate, temporary effect of Pectus-correction. Materials and Methods: We included 26 consecutive patients (mean age is 13,3 + /-2,2 years) symp-tomatic and non, with a previous clinical diagnosis of PE. CMR was performed before and during appli-cation of VB, using the same imaging protocol. In both conditions, we measured thoracic indexes, and cardiac function as well as flow through main vessels. Results: Mean expiratory Haller Index (HI) was 5,4 ( + /-1,4 SD; normal < 3). During VB application, all pa-tients showed improvement in the main morphologic parameters of the thorax (mean expiratory HI = 4,7 ( + /-1,6 SD, delta-13%, P = 0,01). During VB application, a minimal but not significant increase of Right Ventricle End Diastolic Volume (RVEDVi) (delta + 4,6%, P = 0,12), and Right Ventricle Ejection Fraction (RVEF) (delta + 1,2%, P = 0,2) was observed. Conclusion: In adolescents affected by PE, cardiacMRI (CMR) demonstrates normal values of biventricu-lar volume and systolic function. During VB application, beside significative improvements in chest wall anatomy, CMR shows a minimal positive variation in right ventricle volume and function. A minority of patients showed some degree of diastolic dysfunction at baseline, unchanged after VB application, with possible correlation between valve inflow and sternal impingement. (c) 2020 Elsevier Inc. All rights reserved