Background: Vaginal flora abnormalities are common in women in their genitally active period. The aims of this study are to describe vaginal flora abnormalities and genital infections discovered from the Nugent score and to describe the associated factors with these abnormalities. Methods: This is a prospective and descriptive study of the microbiological results of the cervico-vaginal smears from the Nugent score and the microbiological culture for a period of six months from July to December 2019. This study was carried out in the laboratory of the University Hospital Joseph Raseta Befelatanana Antananarivo in Madagascar. Results: Among of the 161 cervico-vaginal smears, the score de Nugent associated of the microbiological results showed 52 (32.3%) cases of intermediate vaginal flora, 47(29.2%) cases of bacterial vaginosis, 46 (28.6%) cases of normal vaginal flora, 13 (8.1%) cases of vaginal candidiasis and 3(1.9%) cases of Staphylococcus aureus vaginitis. Concerning the Nugent score values, scores 4 and 7 are the most common. Concerning the associated factors with these vaginal flora abnormalities, women over 40 years (p=0.20; NS), hospitalized (p=0.25; NS) and suffering from leucorrheas (p=0.02) are the most affected by these abnormalities. Conclusion: Associated with the result of microbiological culture, the Nugent score helps biologists to diagnose genital infections from the cervico-vaginal smear.
