This paper studies the design of cluster experiments to estimate the global
treatment effect in the presence of spillovers on a single network. We provide
an econometric framework to choose the clustering that minimizes the worst-case
mean-squared error of the estimated global treatment effect. We show that the
optimal clustering can be approximated as the solution of a novel penalized
min-cut optimization problem computed via off-the-shelf semi-definite
programming algorithms. Our analysis also characterizes easy-to-check
conditions to choose between a cluster or individual-level randomization. We
illustrate the method's properties using unique network data from the universe
of Facebook's users and existing network data from a field experiment