The retrospective assessment of individual exposure in occupational settings often derives from the association of individual work histories with quantitative and semi-quantitative exposure information. In absence of information on exposure, researchers commonly employed proxy variables, but with strong assumptions and some limitations. In the present work, we propose a new method to estimate the time-varying exposure risk associated to outcomes of interest considering functional regression models and individual work periods. As an illustrating example to understand the potentiality of the method, we analysed a cohort of dock workers occupationally exposed to asbestos in Italy
