Additional file 2: of Identifying and correcting epigenetics measurements for systematic sources of variation

Abstract

Figure S2. Quantile-quantile (QQ) plots for CpG site-specific analysis with respect to smoking using standard adjustment (a), residuals (b), ComBat (c) and SVA (d) correcting methods for the β values. The inflation factor λ is defined as the ratio of the median of the observed log10 transformed p values from the CpG site-specific analysis and the median of the expected log10 transformed p values. (PDF 110 kb