Abstract Social health means the appropriate and desirable role and function of the individual in the society and having appropriate social connections within the social networks in the society. On the other hand, cities, and especially metropolises, are faced with a multitude of social health problems and problems that all affect the individuals' physical and mental health. Due to the increasing importance of social health in the present study, this study aimed to investigate the important social determinants affecting social health. This study was conducted among 400 citizens living in District One of Tehran and was used theoretically to explain the subject from the theoretical point of view of Curie Keys and Shapiro. In the method section, the questionnaire survey and cluster sampling method were used to complete the questionnaire. The results showed that the four variables of social support, quality of life, social security and socioeconomic status all correlated with the dependent variable of social health and the independent variables listed were able to predict the social health variable. Accordingly, the highest predictor was related to the social support variable and then to life satisfaction, social security and socioeconomic status, respectively. Keywords: Social Health, Social Support, Quality of Life, Social Security, and Socioeconomic Status