The Kalman-Bucy filter was applied on the preprocessing of the functional magnetic resonance image-fMRI. Numerical simulations of hemodynamic response added Gaussian noise were performed to evaluate the performance of the filter. After the proceeding was applied in auditory real data. The Kohonen’s self-organized map was employed as tools to compare the performance of the Kalman’s filter with another type of pre-processing. The results of the application of Kalman-Bucy filter for simulated data and real auditory data showed that it can be used as a tool in the temporal filtering step in fMRI data
