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Optimal discrimination designs

Abstract

We consider the problem of constructing optimal designs for model discrimination between competing regression models. Various new properties of optimal designs with respect to the popular TT-optimality criterion are derived, which in many circumstances allow an explicit determination of TT-optimal designs. It is also demonstrated, that in nested linear models the number of support points of TT-optimal designs is usually too small to estimate all parameters in the extended model. In many cases TT-optimal designs are usually not unique, and in this situation we give a characterization of all TT-optimal designs. Finally, TT-optimal designs are compared with optimal discriminating designs with respect to alternative criteria by means of a small simulation study.Comment: Published in at http://dx.doi.org/10.1214/08-AOS635 the Annals of Statistics (http://www.imstat.org/aos/) by the Institute of Mathematical Statistics (http://www.imstat.org

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