Detecting and discovering new gene interactions based on known gene
expressions and gene interaction data presents a significant challenge. Various
statistical and deep learning methods have attempted to tackle this challenge
by leveraging the topological structure of gene interactions and gene
expression patterns to predict novel gene interactions. In contrast, some
approaches have focused exclusively on utilizing gene expression profiles. In
this context, we introduce GENER, a parallel-layer deep learning network
designed exclusively for the identification of gene-gene relationships using
gene expression data. We conducted two training experiments and compared the
performance of our network with that of existing statistical and deep learning
approaches. Notably, our model achieved an average AUROC score of 0.834 on the
combined BioGRID&DREAM5 dataset, outperforming competing methods in predicting
gene-gene interactions