slides

Differences between untransformed and spatially normalized PET images in the functional comparison of schizophrenic patients and controls

Abstract

[Abstract] AMI International Conference 2003, September 21 - 27, Madrid, Spain: "High Resolution Molecular Imaging: from Basic Science to Clinical Applications"A common problem in quantitative studies involving multi-subject analysis of brain functional images is the requirement of a spatial normalization step to provide a standardized reference space. Since SPM is one of the most widely used analytical approaches for functional studies, our aim is to investigate differences in metabolic activity measurements in positron emission tomography (PET) images with or without the spatial normalization performed by SPM. The possible effect of the normalization will be evaluated in a comparison of metabolic activity between schizophrenic patients and controlsPublicad

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