Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity

A Beckett (12638044); A da Silva Filipe (12638050); A Joseph (13423995); A Marchbank (12147654); A Price (9272516); AP Underwood (16722300); B Jackson (730932); B Warne (16722474); BEW Taylor (16722696); C Bresner (16722684); C Fraser (7655042); C Holmes (9860972); C Kitchen (16722669); C Koshy (9883466); C Moore (7713326); CA Yeats (16722690); D Bonsall (16722234); D Jorgensen (9858146); DJ Fairley (16722282); DJ Pascall (16722897); DM Aanensen (16722288); E Volz (16339197); E Wise (13335012); F Coll (16722738); F Sang (16722732); FA Khokhar (16724076); FF Nascimento (16189748); G Clark (7646894); G Nebbia (12638089); H Adams (7756475); H Gulliver (16722672); HC Howson-Wells (16722711); I Merrick (16722675); I Siveroni (16724070); I Willingham (16722717); J Debebe (16722735); J Edgeworth (16722687); J Lynch (95238); J Maksimovic (13435104); J Shepherd (7635521); J Southgate (13709191); J Tang (6098858); JP McKenna (16722648); JT McCrone (16723782); K Abudahab (16722693); K Fallon (13576507); K Li (8012927); K McCluggage (16722663); K Spellman (16722660); KF Loveson (16722309); L Berry (13369704); L Geidelberg (16723767); LB Snell (16722129); M Bull (16363920); M Carlile (13427097); M Guest (13711633); M John (13300485); M Khakh (16722702); M Menegazzo (16722699); M Mori (5804027); M Wantoch (16722657); MM Lister (16722708); MW Loose (16722285); N Cortes (16244663); N Holmes (16200725); N Jesudason (16724064); N Pacchiarini (16722306); N Reynolds (9865202); N Sheriff (16722726); P Bird (9885017); R Batra (13381044); R Beer (11443063); R Jarrett (16724067); R Johnson (7766954); R Munn (16722678); R Shah (7687283); RM Colquhoun (16724061); S Afifi (16722666); S Campbell (7641563); S Kidd (13673821); S Morgan (9848480); SC Robson (14541245); SL Caddy (16724073); SM Nicholls (15791546); SM Rey (16724058); T Boswell (16722714); T Charalampous (12638047); T Curran (13635721); T Golubchik (16193246); T Helmer (16722720); T Workman (16722681); TR Connor (16099502); V Hill (7814726); V Raviprakash (16722723); V Wright (13527622); VM Fleming (16722705); W Fuller (13703857); W Smith (7891619); Á O'Toole (16723428)

Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity

Authors: A Beckett (12638044)
A da Silva Filipe (12638050)
A Joseph (13423995)
A Marchbank (12147654)
A Price (9272516)
AP Underwood (16722300)
B Jackson (730932)
B Warne (16722474)
BEW Taylor (16722696)
C Bresner (16722684)
C Fraser (7655042)
C Holmes (9860972)
C Kitchen (16722669)
C Koshy (9883466)
C Moore (7713326)
CA Yeats (16722690)
D Bonsall (16722234)
D Jorgensen (9858146)
DJ Fairley (16722282)
DJ Pascall (16722897)
DM Aanensen (16722288)
E Volz (16339197)
E Wise (13335012)
F Coll (16722738)
F Sang (16722732)
FA Khokhar (16724076)
FF Nascimento (16189748)
G Clark (7646894)
G Nebbia (12638089)
H Adams (7756475)
H Gulliver (16722672)
HC Howson-Wells (16722711)
I Merrick (16722675)
I Siveroni (16724070)
I Willingham (16722717)
J Debebe (16722735)
J Edgeworth (16722687)
J Lynch (95238)
J Maksimovic (13435104)
J Shepherd (7635521)
J Southgate (13709191)
J Tang (6098858)
JP McKenna (16722648)
JT McCrone (16723782)
K Abudahab (16722693)
K Fallon (13576507)
K Li (8012927)
K McCluggage (16722663)
K Spellman (16722660)
KF Loveson (16722309)
L Berry (13369704)
L Geidelberg (16723767)
LB Snell (16722129)
M Bull (16363920)
M Carlile (13427097)
M Guest (13711633)
M John (13300485)
M Khakh (16722702)
M Menegazzo (16722699)
M Mori (5804027)
M Wantoch (16722657)
MM Lister (16722708)
MW Loose (16722285)
N Cortes (16244663)
N Holmes (16200725)
N Jesudason (16724064)
N Pacchiarini (16722306)
N Reynolds (9865202)
N Sheriff (16722726)
P Bird (9885017)
R Batra (13381044)
R Beer (11443063)
R Jarrett (16724067)
R Johnson (7766954)
R Munn (16722678)
R Shah (7687283)
RM Colquhoun (16724061)
S Afifi (16722666)
S Campbell (7641563)
S Kidd (13673821)
S Morgan (9848480)
SC Robson (14541245)
SL Caddy (16724073)
SM Nicholls (15791546)
SM Rey (16724058)
T Boswell (16722714)
T Charalampous (12638047)
T Curran (13635721)
T Golubchik (16193246)
T Helmer (16722720)
T Workman (16722681)
TR Connor (16099502)
V Hill (7814726)
V Raviprakash (16722723)
V Wright (13527622)
VM Fleming (16722705)
W Fuller (13703857)
W Smith (7891619)
Á O'Toole (16723428)
Publication date: 7 January 2021
Publisher

Abstract

Analysis of the spread and frequency of SARS-CoV-2 D614G in the United Kingdom suggests a selective advantage for this strain that is associated with higher viral loads in younger patients but not higher COVID-19 clinical severity or mortality

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