The aim of this study was to compare the prevalence of risk factors for frailty between
perimenopausal women with long COVID-19 syndrome, women having successfully recovered from
COVID-19, and controls from the community. Women with a diagnosis of long COVID-19 and at
least one symptom related to the perimenopausal period, women who had successfully recovered
from COVID-19, and healthy women of comparable age were included in this study. Symptom
severity and functional disability were assessed with the COVID-19 Yorkshire Rehabilitation Scale,
and the presence of frailty was evaluated considering the Fried criteria. A total of 195 women were
included in the study, distributed over the three groups. The long COVID-19 group showed a higher
prevalence of perimenopausal symptoms and impact of COVID-19. Statistically significant differences
were found between the long COVID-19 group and the other two groups for the frailty variables.
When studying the associations between frailty variables and COVID-19 symptom impact, significant
positive correlations were found. Perimenopausal women with long COVID-19 syndrome present
more frailty-related factors and experience a higher range of debilitating ongoing symptoms. A
significant relationship is shown to exist between long COVID-19 syndrome-related disability and
symptoms and frailty variables, resulting in an increased chance of presenting disability.Formación Profesorado Universitario (FPU)
grant (FPU: 19/02609) from the Spanish Ministry of EducationFPU grant (FPU: 21/00451) for the training of university faculty from the University of
GranadaCollege of Physiotherapists of Andalucia,
(Project Ref: 06195/21D/MA
