In magnetic nanoparticle hyperthermia, the magnetic nanoparticles (MNPs) start oscilla-
tions when they are exposed to an alternating magnetic field, which may generate ultra-
sound waves. These resulting oscillations of nanoparticles can lead to the movement of drug
carrier liposomes. In this study, a multiphysics coupling model of magnetic nanoparticle
behavior in an alternating magnetic field was developed, implementing solid mechanics
compliance parameters and piezomagnetic coupling matrices. A detailed sensitivity study
was conducted to to examine the effects of size and elastic modulus of MNPs, distribution
and distance between two MNPs, elasticity and viscosity of the glycerol medium and mesh
element sizes on the output displacement signals of MNPs. The results indicated that mag-
netic nanoparticles undergo some displacements when they are exposed to an alternating
magnetic field. These oscillations may generate ultrasound waves, though the amount
of displacement for each nanoparticle is negligibly small. It is expected that aggregated
nanoparticles result in much higher oscillations.Ministry of Science and Innovation, Spain grant
numbers PID2019-106947RA-C2FEDER EQC2018-004508-
