Genomics and environmental regulation : science, ethics, and law /

Abstract

To reduce the deleterious effects of environmental contamination, governments across the world have enacted regulations broadly conceived for entire populations. Information arising out of the Human Genome Project and other cutting-edge genetic research is shifting the policymaking process. This fascinating volume draws on experts from academia, government, industry, and nongovernmental organizations to examine the science of genomic research as applied to environmental policy. The first section explores environmental policy applications, including subpopulation genetic profiling, industrial regulations, and standardizing governmental evaluation of genomic data. The second section assesses from multiple angles the legal framework involved in applying genomics to environmental regulation. In the third section, the contributors review closely the implications of genomic research for occupational health, from disease prevention and genetic susceptibility to toxicants, to workers' rights and potential employment discrimination. A fourth section explores the bioethical and philosophical complications of bringing genetic data and research into nonclinical regulatory frameworks.Genomics and Environmental Regulation points to ways in which information on toxicology and genetics can be used to craft more precise and efficient regulations.Includes bibliographical references and index.Genetics and workplace issues / Paul A. Schulte -- Advances in human genome epidemiology: implications for occupational health and disease prevention / Marc Weinstein -- Occupational health and discrimination issues raised by toxicogenomics in the workplace / Mark A. Rothstein -- Genetic susceptibility and radiological health and safety / Kenneth L. Mossman -- Conceptual and normative dimensions of toxicogenomics / Andrea O. Smith and Jason Scott Robert -- Environmental disease, biomarkers, and the precautionary principle / David B. Resnik -- Rights and the exceptionally vulnerable / James W. Nickel -- (Almost) equal protection for genetically susceptible subpopulations: a hybrid regulatory-compensation proposal / Carl Cranor -- Protecting people in spite of, or thanks to, the "veil of ignorance" / Adam M. Finkel.Toxicogenomics and environmental regulation / Gary E. Marchant -- Addressing genomic needs at the U.S. Environmental Protection Agency / Kerry L. Dearfield ... [et al.] -- Application of genomics for health and environmental safety of chemicals: an industry perspective / Richard D. Phillips -- Toxicogenomics and the public interest: technical and sociopolitical challenges / John M. Balbus -- Challenges in applying toxicogenomic data in federal regulatory settings / Lynn L. Bergeson -- Genetic data and toxic torts: intimations of statistical reductionism / Andrew Askland and Gary E. Marchant -- Genomics and environmental justice: some preliminary thoughts / Gary E. Marchant and Jamie A. Grodsky -- Setting air quality standards in the postgenomic era / Gary E. Marchant --To reduce the deleterious effects of environmental contamination, governments across the world have enacted regulations broadly conceived for entire populations. Information arising out of the Human Genome Project and other cutting-edge genetic research is shifting the policymaking process. This fascinating volume draws on experts from academia, government, industry, and nongovernmental organizations to examine the science of genomic research as applied to environmental policy. The first section explores environmental policy applications, including subpopulation genetic profiling, industrial regulations, and standardizing governmental evaluation of genomic data. The second section assesses from multiple angles the legal framework involved in applying genomics to environmental regulation. In the third section, the contributors review closely the implications of genomic research for occupational health, from disease prevention and genetic susceptibility to toxicants, to workers' rights and potential employment discrimination. A fourth section explores the bioethical and philosophical complications of bringing genetic data and research into nonclinical regulatory frameworks.Genomics and Environmental Regulation points to ways in which information on toxicology and genetics can be used to craft more precise and efficient regulations