Background and Objectives: Post-COVID-19 syndrome is commonly used to describe signs
and symptoms that continue or develop after acute COVID-19 for more than 12 weeks. The study
aimed to evaluate a treatment strategy in patients with adhesive capsulitis (phase 1) developed in
post-COVID-19 syndrome. Materials and Methods: The method used was an interventional pilot study
in which 16 vaccinated patients presenting with the clinical and ultrasound features of adhesive
capsulitis (phase 1) developed during post-COVID-19 syndrome were treated with infiltrative hy-
drodistension therapy under ultrasound guidance associated with early rehabilitation treatment.
Results: Sixteen patients with post-COVID-19 syndrome treated with ultrasound-guided infiltration
and early rehabilitation treatment showed an important improvement in active joint ROM after
10 weeks, especially in shoulder elevation and abduction movements. The VAS mean score before the
treatment was 6.9 ± 1.66. After 10 weeks of treatment, the VAS score was 1 ± 0.63. Conclusions: The
study demonstrated that the management of adhesive capsulitis (phase 1) developed in post-COVID-
19 syndrome, as conducted by physiotherapists in a primary care setting using hydrodistension and
a rehabilitation protocol, represented an effective treatment strategy