The main focus of this thesis was to evaluate the effect of corticosteroids in CSDH treatment. The current evidence suggests that corticosteroids should not be used as stand-alone treatment. Furthermore, there is no high-level evidence to use dexamethasone as additional treatment in the standard care of CSDH patients. Burr hole craniostomy is the preferred treatment option in patients with neurological deficits. With an (inter)national collaborative approach and a large-scale prospective registry we will be able to develop more insight and share ideas on new high-quality trials.<br/