The purpose of this study was to clarify the current status of oncology certified nurse specialist(OCNS) involvement in cancer genome medicine. A survey of 235 OCNSs who consented to participate in the study revealed that those involved in cancer genome medicine had a better understanding of hereditary tumors. Through descriptive content analysis, 8 learning needs were identified in relation to cancer genome medicine. Among these needs,[ basic knowledge of hereditary tumors and cancer genome medicine], [regular acquisition of up-to-date information on genetic medicine], and[ genetic counseling in actual clinical settings]revealed no differences between OCNSs involved and not involved in genetic medicine. On the other hand,[ role of an OCNS in genetic medicine], [nursing care for patients and families with hereditary diseases], [systems and collaboration to incorporate genetic medicine into organizations], [information on genetic medicine for facilities other than urban/designated hospitals], and[ programmed learning as a systematic approach to genetic medicine provided by academic societies] differed between the groups in terms of descriptive contents