Arnold, W. David

Singh, Mahendra P.

Srivastava, Amit K.

Tan, Eng King

Zhang, Yiying

BioMed Research International

Harvard University - DASH 

Neurodegeneration: Etiologiesand New Therapies 2016The Harvard community has made thisarticle openly available.  Please share  howthis access benefits you. Your story mattersCitation Tan, Eng King, Amit K. Srivastava, W. David Arnold, MahendraP. Singh, and Yiying Zhang. 2016. “Neurodegeneration:Etiologies and New Therapies 2016.” BioMed ResearchInternational 2016 (1): 8363179. doi:10.1155/2016/8363179. http://dx.doi.org/10.1155/2016/8363179.Published Version doi:10.1155/2016/8363179Citable link http://nrs.harvard.edu/urn-3:HUL.InstRepos:29626120Terms of Use This article was downloaded from Harvard University’s DASHrepository, and is made available under the terms and conditionsapplicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAAEditorialNeurodegeneration: Etiologies and New Therapies 2016Eng King Tan,1 Amit K. Srivastava,2 W. David Arnold,3Mahendra P. Singh,4 and Yiying Zhang51Department of Neurology, Singapore General Hospital, National Neuroscience Institute andDuke NUS Graduate Medical School, Singapore 1698572Department of Pediatric Surgery, University of Texas Health Sciences Center at Houston, Houston, TX 77030, USA3Department of Neurology, Division of Neuromuscular Disorders and Department of PM&R and Department of Neuroscience,The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA4Toxicogenomics and Predictive Toxicology Division, CSIR-Indian Institute of Toxicology Research, Lucknow,Uttar Pradesh 226 001, India5Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School,Charlestown, MA 02129, USACorrespondence should be addressed to Eng King Tan; tan.eng.king@sgh.com.sgReceived 3 October 2016; Accepted 5 October 2016Copyright © 2016 Eng King Tan et al. This is an open access article distributed under the Creative Commons Attribution License,which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.In this special issue, we have 9 articles that highlight diversebiochemical, immunological, molecular, and neuroimagingtechniques used to decipher the pathophysiological mech-anisms underpinning neurodegeneration in various cellularand animal models. The common diseases are covered,including a review on the therapeutic options in Alzheimer’sdisease and a discussion on the factors influencing homo-cysteine levels in Parkinson’s disease. Of particular interestin this issue is an article on the entity of “chemo brain,”a condition that overlaps between oncology and neurology.“Chemo brain” is a common term used to describe thinkingand memory problems that can occur after cancer treatment.Here the authors demonstrate PET evidence of the effectof donepezil on cognitive performance in an animal model.We hope this special issue will generate further interest anddebate on the pathoetiology of neurodegenerative diseasesand provide a platform to generate impetus to further identifyand validate new therapeutic options.Eng King TanAmit K. SrivastavaW. David ArnoldMahendra P. SinghYiying ZhangHindawi Publishing CorporationBioMed Research InternationalVolume 2016, Article ID 8363179, 1 pagehttp://dx.doi.org/10.1155/2016/8363179

Neurodegeneration: Etiologies and New Therapies 2016

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