Extranodal NK/T cell lymphoma, ‘nasal type,’ is a rare
clinicopathological entity in Europe. The main clinical features are
nasal congestion, sore throat, dysphagia and epistaxis, due to a
destructive mass involving the midline facial tissues. Pathologically,
lymphoma cells exhibit angioinvasion, angiodestruction and coagulative
necrosis. We report the case of a patient who presented with fever,
dyspnea, nasal congestion, headache, distention of right nasal
turbinates and exophytic lower leg ulcerating lesions. A CT scan of
visceral scull demonstrated a filling mass of right frontal, ethmoidal
and maxillary sinuses with erosion of the wall of right maxillary sinus
and ventral portion of the diaphragm. A biopsy was performed in the skin
lesion and showed an angioinvasive NK/T cell lymphoma CD56 negative with
clonal rearrangement of the T-cell-receptor gamma gene. Up to our
knowledge, this is a rare immunophenotype for NK/T-cell, ‘nasal type,’
lymphomas. However, the lymphoma may be classified as extranodal NK/T
cell lymphoma, ‘nasal type,’ due to typical clinical presentation,
radiologic findings and pathological characteristics of polymorphism,
angioinvasion, angiodestruction and coagulative necrosis
