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Involvement of E2F transcription factor family in cancer
Authors
P.K. Tsantoulis Gorgoulis, V.G.
Publication date
1 January 2005
Publisher
Abstract
The E2F family of transcription factors is a central modulator of important cellular events, including cell cycle progression, apoptosis and DNA damage response. The role of E2F family members in various human malignancies is yet unclear and may provide vital clues to the diagnosis, prognosis and therapy of cancer patients. In this review we provide a brief but concise overview of E2F function and its putative role in the most common human tumour types. © 2005 Elsevier Ltd. All rights reserved
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Pergamos : Unified Institutional Repository / Digital Library Platform of the National and Kapodistrian University of Athens
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Last time updated on 10/02/2023