https://openworks.mdanderson.org/sumexp23/1022/thumbnail.jp

Austin, Mary T

Basta, Anthony V

Fritz, Connor D

English

OpenWorks @ MD Anderson

Background• Osteosarcoma is the most common malignancy of bone1• Survival rates for osteosarcoma are around 70%2• There has been little study of associations between patient characteristics, tumor features, and outcomes in pediatric osteosarcomaAssociations between Sociodemographics and Pediatric Osteosarcoma CharacteristicsConnor Fritz1, 2, Anthony Basta1,2, Mary Austin1,21. The University of Texas MD Anderson Cancer Center2. University of Texas Health Houston, McGovern Medical SchoolReferences1. Damron T, Ward W, Stewart A (2007). Osteosarcoma, chondrosarcoma, and Ewing’s sarcoma: National cancer data base report. Clinical Orthopaedics and Related Research2. Siegel R, Miller K, Wagle N, Jemal A (2023). Cancer Statistics, 2023. CancerPurpose• Predictor variables: sex, age group, race/ethnicity, county SES, rurality• Outcome variables: tumor size, tumor site, metastases, chemotherapy, amputation, treatment time, survival• How are these variables related?Methods• Surveillance Epidemiology and End Results: a national cancer registry• Patients ages 0-24• Samples from 2004-2020• 2391 osteosarcoma cases• Multivariate logistic regression to assess tumor features/treatment• Multivariate Cox regression to assess cause-specific survivalConclusion• Numerous disparities in pediatric osteosarcoma presentation, treatment and survival• Differences occur across sex, race/ethnicity, age group and rurality• Further work is needed to explain and address these disparitiesPresentationTreatmentSurvivalMetastases Tumor LocationTumor SizeReference GroupsAmputation Chemotherapy Time from Diagnosis to TreatmentSurvival, No Stage Survival, With StageSample DemographicsAge Race and Ethnicity Sex57% 43%Sex: maleRace/Ethn.: Non-Hispanic WhiteAge Group: 0-10County Income: >$50000County Rurality: urbanModified Stage: localPrimary Site: extremity

Associations between Sociodemographics and Pediatric Osteosarcoma Characteristics

https://openworks.mdanderson.org/cgi/viewcontent.cgi?article=1022&context=sumexp23

Associations between Sociodemographics and Pediatric Osteosarcoma Characteristics

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