Cardiovascular disease is a serious threat to human life and health. The number of people who die from cardiovascular disease is up to 15 million every year, ranking the first cause of all causes of death. ADAMTS family (A Disintegrin and Metalloproteinase With Thrombospondin Motifs, ADAMTSs) are matrix-associated zinc metallopeptidases with secretory function. It has diverse roles in tissue morphogenesis, pathophysiological remodeling, inflammation, and vascular biology. Controlling the structure and function of the Extracellular Matrix (ECM) is the central theme of the biology of ADAMTSs. ADAMTSs mainly play a biological role by regulating the structure and function of extracellular mechanisms, and the abnormal expression or dysfunction of some family members is associated with cardiovascular diseases. ADAMTS family plays an important role in the occurrence and development of various cardiovascular diseases. This paper aims to study the role of ADAMTS family in cardiovascular diseases
