Objective: To observe the effectiveness of different medication regimens in the treatment of asthma diseases. Methods: Sixty-four patients with asthma who attended the medical records department from 2020.6 to 2022.8 were analyzed. 32 patients in group A were treated with methylprednisolone alone, while group B was treated with intravenous amiloride injection in addition to the medication regimen in group A. The improvement time of symptoms in each group was observed, the total effective rate was calculated and the differences between groups were analyzed. Results: In Group B, the improvement time of wheeze, cough, croup and wet rales was earlier than that in Group A (P＜0.05). In terms of total effective rate, the difference was 65.63% vs. 93.75% in group A vs. group B (P < 0.05). Conclusion: The combination of methylprednisolone and ambroxol injection in the treatment of asthma can provide more rapid relief of symptoms and improve the efficacy, which is worth promoting
