Objective: This study mainly analyzes the effect of rehabilitation training on limb function and self-care ability of Parkinson's disease patients. Methods: 50 patients with Parkinson's disease who were diagnosed and treated in a Shaanxi Provincial People's Hospital in China from February 2, 2018 to July 2, 2021 were tested. These patients were divided into two groups randomly with 25 patients in each group. The control group should adopt routine treatment and nursing intervention, and the experimental group should take the control group as the benchmark and apply rehabilitation exercise training, The limb function and self-care ability of patients in the experimental group were compared with control group before and after the intervention. Results: after the intervention, the patients in the control group, whether Berg balance scale or UPDRS - â…¢ score, will be lower than the patients in the observation group. And after the intervention, the Barthel score of both groups will be better than that before the intervention (P < 0.01). Conclusion: rehabilitation training has a great impact on the limb function and self-care ability of patients with Parkinson's disease. Through the form of rehabilitation exercise training, we can further improve the limb function of current patients, make the self-care ability of patients become higher, and delay the development of the disease