This paper examines ten possible topological interpretations of connection and for each interpretation, identifies sufficient conditions under which a significant class of topological spaces provides models of General Extensional Mereotopology with Closure Conditions (GEMTC) in which some key mereotopological ideas align with their topological analogues. In particular, there is an interpretation under which the non-empty sets of any symmetric topology are a model of GEMTC with alignment between the mereotopological and topological definitions of (self-)connection, open and closed entities, interior, exterior, closure, and boundary
