Nowadays employment of dental resins of different types has become a standard procedure. Providing a complete characterization of their mechanical behaviour is mandatory to improve their characteristics, design, and usage. In this study, we applied the nanoindentation technique to obtain experimental data to be fitted. Then, a genetic algorithm combined with a gradient algorithm were applied to find the best set of the mechanical
parameters that characterize the Burger model in series with a frictional element, able to predict the nanoindentation process. Furthermore, with this approach one type of test permits to obtain mechanical parameters useful to characterize the viscoelastoplastic response of these materials