Yildirim, Onur

English

Institutional Research Information System University of Turin

16 October 2023AperTO - Archivio Istituzionale Open Access dell'Università di TorinoOriginal Citation:Triazine-based 2D-covalent organic frameworks enhances electrochemical performance ofenzymatic biosensorsTerms of use:Open Access(Article begins on next page)Anyone can freely access the full text of works made available as "Open Access". Works made availableunder a Creative Commons license can be used according to the terms and conditions of said license. Useof all other works requires consent of the right holder (author or publisher) if not exempted from copyrightprotection by the applicable law.Availability:This is a pre print version of the following article:This version is available http://hdl.handle.net/2318/1705616 since 2019-07-05T19:26:46ZTriazine-Based 2D-Covalent Organic Frameworks Enhances Electrochemical Performance of Enzymatic Biosensors                                                        Onur Yildirim,a Burak Derkusb aDepartment of Chemistry, University of Turin, Via Pietro Giuria 7, 10125/Torino, Italy  bDepartment of Chemistry, Science Faculty, Ankara University, 06100/Ankara, Turkey Email: onryildirim@outlook.com   Well-ordered two dimensional porous materials such as zeolites, covalent organic frameworks (COFs) and metal organic frameworks (MOFs) have impressed remarkable attention thanks to their great numbers of existing and potential applications. While researchers have utilized from these materials for the purpose of energy storage, optoelectronics or even drug delivery, there have been only a couple studies dealing with biosensor applications of organic frameworks [1, 2], yet, best to our knowledge, there have not been a study that uses COFs as biosensor matrix. In this study, we have focused on the synthesis and characterization of triazine based COFs (CTF-1), followed by application towards electrochemical enzymatic biosensors. We firstly modified screen-printed carbon electrode surface with gelatine-CTF-1 gel, and immobilized superoxide dismutase (SOD) enzyme, that catalyzes the dismutation reaction of superoxide radicals (O2-.) into H2O2. Electrochemical impedance spectroscopy measurements showed that the charge transfer resistance (Rct) of gelatine-CTF-1 modified electrode was nearly 21.7% lower than that gelatine modified electrode (Figure 1A). The amperometric spectrum demonstrated that the gelatine-CTF-1-SOD electrode showed an amperometric response that was 25.4% higher than that gelatine-SOD modified electrode (Figure 1B). These findings suggest that CTF-1 is a promising candidate to be used as electrochemical enzymatic biosensor component.   Figure 1: (A) EIS spectra, and (B) Amperometric spectra of gelatine-CTF-1-SOD biosensor  [1] Miller SE, Teplensky MH, Moghadam PZ, Fairen-Jimenez. Interface Focus. 2016 Aug 6;6(4):20160027. [2] Xiao-Qin Wu,  Jian-Gong Ma,  Han Li,  Di-Ming Chen,  Wen Gu,  Guang-Ming Yang  and  Peng Cheng. Chem. Commun., 2015,51, 9161-9164   

Triazine-based 2D-covalent organic frameworks enhances electrochemical performance of enzymatic biosensors

https://iris.unito.it/bitstream/2318/1705616/1/ABS_YILDIRIM.ONUR.pdf

Triazine-based 2D-covalent organic frameworks enhances electrochemical performance of enzymatic biosensors

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