Educational innovation often builds on existing practices, and focuses on improvement, rather than a radical change. One current example of educational innovation is Challenge-Based Learning (CBL). At university [blinded] the approach is a curriculum wide implementation of CBL based on a integrated programme that combines implementation of bottom-up innovation projects with research. The result of this research contributes to the translation of CBL to practice, thus helping curriculum designers and teachers in designing and executing their courses. In the process evidence is collected about principles of CBL, learning behaviour, learning outcomes, and didactical aspects of CBL, such as coaching and self-directed learning, assessment, pedagogies, and design of challenges, and facilitating structures. The goal of this paper is to explore the development of a research agenda, which aligns research and practice, and to contribute to evidence for successful CBL implementation as result. The CBL research agenda shows which topics and aspects of CBL are addressed by research and practice, and which are overlooked. It is a systematic way of collecting strategic and practical problems related to CBL implementation, and how these are translated into research questions, methods, and results. The CBL research agenda leads to dialogue, which in turn guides our CBL programme. This integrated programme, including the research agenda is governed by a Taskforce CBL and supported by programme management, and a university wide research community. This approach enables the curriculum wide implementation and research of CBL as a concept for educating engineers of the future and strengthening on-campus education
