We generate a new tamoxifen-inducible mice model of EC-specific ErbB3 overexpression to investigate the role of ErbB3 in myocardial ischemia and heart failure. In the present study, we compared cardiac function and fibrosis development in EC cell-specific ErbB3 overexpressing mice versus control after the Isoproterenol (ISO)-induced model of cardiac injury, which culminates in cardiac fibrosis development.https://knowledgeconnection.mainehealth.org/lambrew-retreat-2023/1011/thumbnail.jp
