9000399500957

Eri Miyamoto-Mikami

Hirofumi Zempo

Hiroshi Kumagai

Hiroyuki Tomita

Kosuke Hirata

Makoto Fukuo

Mutsumi Harada

Naokazu Miyamoto

Naoki Kikuchi

Nobuhiro Kamiya

Noriyuki Fuku

Seiji Maeda

Tomoko Kaneko

Wataru Kawai

Yuko Shintake

English

Tokyo Seiei College Repositories / 東京聖栄大学 リポジトリ

－ 1 － 再録 報文 Eur J Sport Sci. 2022 Jun 13; 1-9. Genetic polymorphisms related to muscular strength and flexibility are associated  with artistic gymnastic performance in the Japanese population  Hiroshi Kumagai1,2, Tomoko Kaneko3, Yuko Shintake1,4,  Eri Miyamoto-Mikami1, Hiroyuki Tomita1, Makoto Fukuo1,  Wataru Kawai1, Mutsumi Harada1, Naoki Kikuchi5,  Nobuhiro Kamiya6, Kosuke Hirata7, Hirofumi Zempo8,  Seiji Maeda4,7, Naokazu Miyamoto1, Noriyuki Fuku1 1 Juntendo University. 2 University of Southern California. 3University of Tsukuba. 4University of Tsukuba. 5 Nippon Sport Science University. 6 Tenri University. 7 Waseda University. 8 Tokyo Seiei College..  Abstract This study aimed to examine how genetic polymorphisms related to muscular strength and flexibility influence artistic gymnastic performance in an attempt to identify a novel polymorphism associated with flexibility.  In study 1, the passive straight-leg-raise (PSLR) score and aromatase gene CYP19A1 rs936306 polymorphism, a key enzyme for estrogen biosynthesis, were assessed in 278 individuals. In study 2, athletes (281 gymnasts and 1908 other athletes) were asked about their competition level, and gymnasts were assessed using the difficulty score (D-score) for each event. Muscular strength- (ACTN3 R577X rs1815739 and ACE I/D rs4341) and flexibility-related (ESR1 rs2234693 T/C and CYP19A1 rs936306 C/T) genetic polymorphisms were analyzed.  In study 1, males with the CYP19A1 CT + TT genotype showed significantly higher PSLR scores than those with the CC genotype. In study 2, male gymnasts with the R allele of ACTN3 R577X showed a correlation with the floor, rings, vault, and total D-scores. In addition, male gymnasts with the C allele of ESR1 T/C and T allele of CYP19A1 C/T polymorphisms were correlated with the pommel horse, parallel bars, horizontal bar, and total D-scores. Furthermore, genotype scores of these three polymorphisms correlated with the total D-scores and competition levels in male gymnasts. In contrast, no such associations were observed in female gymnasts.  Our findings suggest that muscular strength- and flexibility-related polymorphisms play important roles in achieving high performance in male artistic gymnastics by specifically influencing the performance of events that require muscular strength and flexibility, respectively.  Highlights: Estrogen-related CYP19A1 polymorphism is a novel determinant of flexibility in males. Muscular strength- and flexibility-related polymorphisms play important roles in high performance in male artistic gymnastics. Genotypes of ACTN3 R577X, ESR1 rs2234693, and CYP19A1 rs936306 may contribute to training plan optimization and event selection in artistic gymnastics.   － 16 －

Genetic polymorphisms related to muscular strength and flexibility are associated with artistic gymnastic performance in the Japanese population

https://tsc.repo.nii.ac.jp/record/2000011/files/紀要 第15号 WEB用PDF_Part21.pdf

Genetic polymorphisms related to muscular strength and flexibility are associated with artistic gymnastic performance in the Japanese population

Abstract

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Tokyo Seiei College Repositories / 東京聖栄大学リポジトリ

Genetic polymorphisms related to muscular strength and flexibility are associated with artistic gymnastic performance in the Japanese population

Abstract

Similar works

Full text

Available Versions

Tokyo Seiei College Repositories / 東京聖栄大学 リポジトリ

Tokyo Seiei College Repositories / 東京聖栄大学リポジトリ