9th International Conference on Systems Biology, ICSB 2008, 22-28 August, Goteborg, SwedenBaSysBio adopts a systems biology approach in which quantitative experimental data will be generated for each step of the information flow and will fuel computational modelling. High throughput technologies (living cell arrays, tiling DNA microarrays, MDLC proteomics and quantitative metabolomics) will be developed in conjunction with new computational modelling concepts to facilitate the understanding of biological complexity. Models will simulate the cellular transcriptional responses to environmental changes and their impact on metabolism and proteome dynamics. The iterative process of simulations and model-driven targeted experiments will generate novel hypotheses about the mechanistic nature of dynamic cellular responses, unravel emerging systems properties and ultimately provide an efficient roadmap to tackle novel, pathogenic organismsN
