Sestre Milosrdnice University hospital and Institute of Clinical Medical Research
Doi
Abstract
The aim of the study was to determine the most common precipitating factors and
symptoms of diabetic ketoacidosis and the possible difference according to age, gender and severity of
diabetic ketoacidosis. Medical records from January 1, 2017 until December 31, 2019 were reviewed
and patients diagnosed with diabetic ketoacidosis were selected. The study included 52 patients, median
age 34 (interquartile range 21-56) years. There was no statistically significant difference between
male and female gender. The severity of diabetic ketoacidosis was moderate in the majority of cases
(65.4%; p=0.005). The most common precipitating factor was infection (61.7%). In patients with
moderate diabetic ketoacidosis, respiratory infections were more common, while gastrointestinal infections
were more common in severe diabetic ketoacidosis (33% and 25%, respectively; p=0.03). Nausea
(median age 32 years; p=0.004) and vomiting (median age 31 years; p=0.01) were more common in
younger age groups, while altered mental status was more common in the older age group (median age
61 years; p=0.001). Infection was the most common precipitating factor. The most common symptoms
in younger age groups were nausea and vomiting, and altered mental status in the older age group.Cilj istraživanja je bio utvrditi najčešće precipitirajuće čimbenike i simptome dijabetičke ketoacidoze te postoji li razlika
s obzirom na dob, spol i stupanj dijabetičke ketoacidoze. Pregledana je medicinska dokumentacija od 1. siječnja 2017. do 31.
prosinca 2019. godine te su izdvojeni bolesnici s dijagnozom dijabetičke ketoacidoze. U istraživanje je uključeno 52 bolesnika.
Medijan dobi bio je 34 godine (interkvartilni raspon 21-56 godina). Nije postojala statistički značajna razlika muškog i
ženskog spola. U najvećem broju slučajeva radilo se o umjerenom stupnju dijabetičke ketoacidoze (65,4%; p=0,005). Najčešći
precipitirajući čimbenik bila je infekcija (61,7%). Kod umjerenog stupnja najčešće se radilo o respiracijskim infekcijama, a
u teškom stupnju o gastrointestinalnim infekcijama (33% i 25%; p=0,03). U mlađim dobnim skupinama češće su se pojavljivale
mučnina (medijan dobi 32 godine; p=0,004) i povraćanje (medijan dobi 31 godina; p=0,01), a u starijoj dobnoj skupini
poremećaj svijesti (medijan dobi 61 godina; p=0,001). Infekcije su bile najčešći precipitirajući čimbenik dijabetičke ketoacidoze.
Najčešći simptomi u mlađim dobnim skupinama bili su mučnina i povraćanje, a u starijoj dobnoj skupini poremećaj
svijesti
