One of the ten global problems of modern medicine behind the tribute of the World Health Organization is the growing antibiotic resistance (ABR) and the growing number of multi-resistant strains of bacteria. So, for the rest of the estimates in 2019, 1.27 million deaths in the whole world were directly related to infections resistant to drug diseases. For forecasts up to 2050, the ABR may predict up to 10 million deaths on a random basis. If you don't make any attempts to fight back from the ABR, you could end up wasting $3.4 trillion in US GDP on the river and throwing another 24 million people into extreme poverty in the coming decade. It is urgent to search for new compounds that can have an antibacterial effect on bacteria, especially multi-resistant strains that pose a threat to human health and safety, among which are E.coli, K.pneumonia, P.aeruginosa. Promising in this direction are chemical compounds - derivatives of ammonium hexafluorosilicate (AHFS). Aim – study of antibacterial activity of AHFS against multiresistant strains of bacteria