Genomic overlap between age at onset of Parkinson Disease and blood platelet parameters variability

Abstract

Common neurodegenerative disorders have been long-hypothesized to be linked with blood platelet biology. Genomic approaches have been recently used to unravel a possibly shared genetic basis between neurodegenerative risk and platelet parameters. A significant though moderate genetic correlation between Parkinson Disease (PD) risk and an index of platelet size variability, has been reported