We consider a class of abstract evolution reaction-diffusion systems with delay and nonlocal initial data of the form ⎩⎨⎧u′(t)∈Au(t)+F(t,ut,vt)v′(t)∈Bv(t)+G(t,ut,vt)u(t)=p(u,v)(t)v(t)=q(u,v)(t)amp;for t∈R+,amp;for t∈R+,amp;for t∈[−τ1,0],amp;for t∈[−τ2,0], where τi≥0, i=1,2, A and B are two m-dissipative operators acting in two Banach spaces, the perturbations F and G are continuous, while the history functions p and q are nonexpansive functions with affine growth. We prove an existence result of C0-solutions for the above problem and we give an example to illustrate the effectiveness of our abstract theory