This work proposes a new methodology to investigate the potential for disconnection (Type III
endoleak) of pairs of overlapped endoprostheses in a popliteal model vessel after a cyclic
physiologic load, for three different overlap lengths. A multiaxial fatigue accelerated testing
was designed to mimic the physiological loads and movements to which the peripheral arteries
are submitted during gait. The experiment design was based on principles from technical
standards ASTM F2477-07 and ASTM F2942-13. Migration and disconnection were
monitored by DIC (Digital Image Correlation) for three different overlap lengths (20, 30 and
40mm). The testing method proposed in this work was efficient to provide a simulated
environment to evaluate the influence of gait biomechanics on overlapped endoprosthesis
disconnection. Obtained results demonstrated minimal or absence of relevant migration
between the endoprosthesis, range -0.06 to 0,34 millimeters. The proposed methodology was
verified as a valuable tool to investigate the influence of the biomechanical environment which
the devices are subjected to on the migration of overlapped endoprosthesis. It may become a
new alternative to study the pre-clinical in vitro performance of single endoprosthesis or
multiple connected devices with different overlapped regions
