The MALTA family of depleted monolithic Pixel sensors produced in TowerJazz 180 nm CMOS technology target radiation hard applications for the HL-LHC and beyond. Several process modifications and front-end improvements have resulted in radiation hardness up to 2e15 n/cm2 and time resolution below 2 ns, with uniform charge collection efficiency across the Pixel of size 36.4 x 36.4 um2 with a 3 um2 electrode size. This contribution will present the results from new cascoded front-end flavour that further reduces the RTS noise and improves the threshold reach, and the comparison of samples produced on high-resistivity epitaxial silicon with Czochralski substrates