The introduction of the tridimensional (3D) organoids technology is revolutionizing the fields of developmental and stem cell biology and it is emerging as the latest frontier in regenerative medicine for the treatment of neurodegenerative disorders, such as epilepsy. The overall objective of my PhD thesis was to set the stage to develop functional hippocampal brain organoid that can be used for regenerative medicine to cure the Temporal Lobe epilepsy (TLE)
