Spencer S. Eccles Health Sciences Library, University of Utah
Abstract
Restoration of vision in patients blinded by advanced optic neuropathies requires therapies that promote retinal ganglion cell (RGC) survival and direct RGC axon regeneration. Previously, we showed that electric fields (EFs) direct RGC axon growth towards the cathode (negative electrode), in vitro. Here, we hypothesized that exogenous application of EFs can be exploited to direct optic nerve regeneration in vivo